Leda Papaconstantinou was born in Ambelona, Larissa in 1945.
Her studies include a Degree in Graphic Design, A.T.I. (Athens Technological Institute Doxiadis), Athens, Greece (1962 – 1965), a BA (Hons) Fine Arts, Maidstone College of Art (K.I.A.D. – Kent Institute of Art and Design, University of Kent), Maidstone, UK (1968 – 1971), and she attended A.S.F.A., Athens School of Fine Arts, Athens, Greece (1965 – 1966) and Loughton College of Art, London, UK (1967 – 1968).
Since 1969 and until now she has shown her work in various group and solo exhibitions, in Greece and abroad. Leda represented Greece at the Sao Paolo Biennale in 1989, at BIDA-Biennale in Seville, Spain in 2005, at the 1st Biennale of Contemporary Arts in Thessaloniki, at the Contemporary Art Biennale in Tashkent, Uzbekistan in 2007, at Live Art on Camera, SPACE London 2007, and at Aisxylia Festival of Performing and Visual Arts in Eleusis, Greece in 2009. Additionally, she has participated in many international art fairs, such as ARCO, Art Frankfurt και FIAC. Her artworks are in various art collections, private and public, in Greece and abroad, namely: the National Gallery, Athens, MOMUS, Thessaloniki, Contemporary Art Museum, Rethymnon, EMST, Athens, Leonidas Beltsios, Dimitris Daskalopoulos, Prodromos Emfientzoglou, Dimosthenis Kanakis, Florika Kyriakopoulou, Eleni Martinou, Dimitris Pieridis, Zaharias Portalakis, Ileana Tounta, Alpha Bank, Nestle. In 2020, she directed 'Sketches on Mediterranean Desert', a video on a cycle of pieces by the composer Giorgos Koumentakis. She also took part, together with Lizzie Calligas, in the 'Two Doors, Two Windows' exhibition at the Ecclesiastical Museum of Spetses. In 2022, she created the sound work 'The Scarf – A Performance to Be Visualised' as part of the hybrid exhibition 'Sheltered Gardens'. In 2023, the National Museum of Contemporary Art in Greece (EMST) presented a major retrospective exhibition for Leda Papaconstantinou, considering her one of the most important artists in the history of contemporary art in Greece.